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These medications are administered via subcutaneous injection, typically weekly for semaglutide and dulaglutide, or daily for liraglutide
In addition, GLP-1 therapies appear to promote natriuresis, or increased sodium excretion, through effects on the kidneys
Your prescriber will follow the licensed guidance whilst tailoring the approach to suit you
This is why a slow titration schedule, spending at least four weeks at each dose level, is recommended
doi:10.2337/dc25-S008.Opens in a new tab Wilding JPH, Batterham RL, Calanna S, et al
Further studies, including final evaluations from regulatory bodies, are warranted to discard a causal link between GLP-1RA and suicidality (shortly before publication of this article, EMA released a news report in line with our findings [39])
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