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Oligomerization of a glucagon-like peptide-1 analog: bridging experiment and simulations

Non-pharmacological therapies, such as food, dietary supplements, and herbal medicines, are frequently chosen over pharmacological treatments despite their potential adverse effects

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For RPA foci, cells were incubated for 3 h after irradiation and then pre-extracted with buffer I (10 mM PIPES pH 7.0, 100 mM NaCl, 300 mM sucrose, 3 mM MgCl2, 1 mM EGTA and 0.5% Triton X-100), followed by buffer II (10 mM Tris pH 7.5, 10 mM NaCl, 3 mM MgCl2, 1% Tween-40 and 0.5% sodium deoxycholate), as previously 42

[53] Van Ameringen, M

Most obesity medicine literature focuses on GLP-1 monotherapy or dual-peptide protocols (semaglutide plus tirzepatide), which show superior long-term efficacy and safety profiles without the cardiovascular burden of sympathomimetic agents