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Its binding constant (pKa 16.44) is similar to albumin's copper transport site (log = 16.2), allowing GHK to exchange copper with albumin for intracellular delivery.[3] Discovery and design rationale GHK was first identified in 1973 in fractions of human plasma that promoted survival of liver cells in culture
doi: 10.1038/SJ.GENE.6364106 59 LuckettAMWeedonMNHawkesGLeslieRDOramRAGrantSFA
8 , eabo6693 (2022)
doi:10.1016/j.celrep.2023.113587 6
DSIP is least relevant as a standalone insomnia treatment in patients without metabolic context
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