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Endogenous lung glutathione does not make nebulisation risk free The chemical environment of an inhaled solution, oxidation products and sulphite sensitivity can affect airway responses

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From a product-use perspective, the practical benefits of a high-purity, lyophilized peptide format include improved stability during shipping and storage, easier long-term keeping when stored correctly, and more consistent reconstitution compared with non-lyophilized solutions

Further, PLB significantly reduced ROS levels in KGN cells, while YTHDF1 overexpression significantly increased ROS generation (Fig