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It's important to understand the difference between "after first use" storage for multi-dose pens versus allowable time at room temperature before use for single-dose pens

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Am J Audiol 32(3S):746760 Jeong H-J, Choi Y, Kim M-H, Kang I-C, Lee J-H, Park C, Park R, Kim H-M (2011) Rosmarinic acid, active component of Dansam-Eum attenuates ototoxicity of cochlear hair cells through blockage of caspase-1 activity