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The authors concluded that glutathione, with or without vitamin C and NAC, was well tolerated but did not produce measurable therapeutic benefit in this cohort (Williams et al., 2025)

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Potential benefit - A patient whose biomarkers suggest rapid metabolism of GLP-1 drugs might be offered a longer-acting formulation, while someone with strong GIP responsiveness could start on a dual-agonist right away, avoiding months of trial-and-error

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Jan 2013;100(2):174-181