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Deficient synthesis of glutathione underlies oxidative stress in aging

Although rapalogs and other mTOR inhibitors have not shown efficacy in reducing the viral reservoir in vivo to date, the importance of cell metabolism in HIV replication and latency should not be overlooked when developing new HIV-1 cure strategies

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Summary Keywords nitric oxide, polyamines, polyamine-derived GABA, metabolism, behavior, sleep, addiction, learning Citation Bedont JL (2025) Nitrogen waste metabolism as a locus of nitrergic co-transmission in the brain