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The PERK/eIF2alpha/ATF4 module of the UPR in hypoxia resistance and tumor growth

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AstraZeneca is currently applying this framework to guide its R&D teams, and although it is too early to demonstrate whether this has improved the company's R&D productivity, we present our data and analysis here in the hope that it may assist the industry overall in addressing this key challenge

1 2 Birkhead 1991, pp

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Remarkably, 89% and 93% of participants achieved liver fat normalization ( 85% of high-dose recipients