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It also means reaching clinically meaningful thresholds, like a 10% or 20% reduction, sooner, which translates to earlier improvements in comorbidities like type 2 diabetes, hypertension, and sleep apnea

Dixon JB

This was what happened with my sonbefore we realized these were night terrors and wed try to reassure him, he would just shout No! to everything we said and continue to cry

Secondary endpoints include change in neural response to visual food cues and to sweet-tasting substances as assessed by functional MRI, change in body weight, change in fat mass and change in eating behaviour and food intake