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Elife 5 , e11123 (2016)

In preclinical studies, 5-Amino-1MQ provides a powerful tool to dissect the cellular and molecular consequences of NNMT inhibition

That is a meaningful shift for the clinical compounding ecosystem but it is not the same as FDA approval of a finished drug product

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A diagnostic trial utilizing physiologic doses of vitamin B12 (1 mcg daily) and observing daily reticulocyte counts after establishing a baseline may also be performed