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How to maximally inhibit tumor growth without interfering with normal physiological activities is a key issue in the development of IGF-1/2 inhibitors

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This is a long-standing and essential part of pharmacy, often used for patients who have allergies to certain dyes or fillers or who need a specific dosage not commercially available

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The available animal studies were not sufficient to resolve this concern because they did not provide a comprehensive dose-ranging, long-term carcinogenicity programme