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Over time, this disrupts blood sugar regulation, suppresses immune surveillance, impairs collagen synthesis, and weakens bone, muscle, and connective tissue integrity

Laruelle, M., Abi-Dargham, A., Gil, R., Kegeles, L

doi: 10.11002/fsp.2024.31.2.287 287 LabharAAhidarNEl-MernissiYBenamariOAit AllaKJahjahSet al

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Mechanistically, FSP1 reduces CoQ and vitamin K, generating radical-trapping antioxidants (RTAs) that effectively terminate lipid peroxidation chain reactions at the plasma membrane, thereby guarding against ferroptosis