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Abnormal Cell Signaling Pathways: The epithelial growth factor receptor (EGFR), part of the human epidermal growth factor receptor (HER) family (Yang and Chang, 2018) and transmembrane receptor tyrosine kinase family (Singal et al., 2019), can become abnormal through gene amplification, mutation, or overexpression

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This combination ensures not only nerve health but also sustained and efficient cellular energy production

The BBB is a cellular structure formed by the neurovascular unit (NVU) and is organized by a monolayer of endothelial and mural cells

doi: 10.1183/23120541.00141-2021 248 BatemanLBestedACBonillaHFChhedaBVChuLCurtinJMet al