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In: Kramer K, Hoppe P, Packer L (eds) 2 NIH 3

4,8 A course of broad-spectrum antimicrobial therapy should include coverage targeting anaerobic microorganisms (i.e., ciprofloxacin plus metronidazole or amoxicillin/clavulanate plus metronidazole)

Beyond Basal Insulin When treatment is intensified beyond basal insulin therapy, a number of factors should be taken into account as part of the shared decision-making process, such as patient preference, safety, tolerability, glycemic efficacy, risk of hypoglycemia, and other non-glycemic effects (e.g., weight change and/or impact on life-style) [13]

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However, lifestyle factors often start to take a toll

We look forward to more reports on metformin-naive patients in published studies and even more new RCTs to further support our current observations