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References 2019 The Author(s)

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70 PARP1 is the best characterized and most studied member that is involved in repairing single strand breaks (SSBs)

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10.1016/j.ijantimicag.2020.106191 96 WeichmannF.RohdewaldP

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Dose: 2mg twice daily (4mg total) Frequency: Morning and evening Duration: 4-6 weeks maximum Rest period: Equal to cycle length Splitting doses maintains more stable plasma levels throughout the day

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Pharmacokinetics and pharmacodynamics of mibavademab (a leptin receptor agonist): results from a first-in-human phase I study

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