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A randomized, placebo-controlled pilot study examined adding phentermine to liraglutide (a GLP-1 agonist similar in class to tirzepatide) in adults with obesity who had already been on liraglutide for one year and achieved approximately 12% weight loss

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Datasets for survival, metabolomics, and cytokines are available here: [ Code availability The R code for survival and metabolomic analyses are available here: [ References Kenyon, C., Chang, J., Gensch, E., Rudner, A

To identify POMC neurons and GLP-1 receptor-positive neurons, POMC humanized Renilla green fluorescent protein (hrGFP) (The Jackson Laboratory, 006421) and GLP-1 receptor cre::tdTomato (The Jackson Laboratory, 029283) mice were used

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