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The high prevalence reported in these studies, however, could be related to the use of ACTH levels for the diagnosis of CAI, rather than 11-deoxycortisol, and the high cut-off used (33 pmol/l) (54, 57, 61)
Key findings for semaglutide duration include continued weight loss through at least 68 weeks with no plateau in many patients, weight regain of approximately 40% of lost weight within seven months of stopping, and withdrawal effects including increased appetite, food cravings, and in some cases gastrointestinal changes