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Verglichen mit der intravensen Injektion derselben Dosis von Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH betrug die mittlere Bioverfgbarkeit des Peptids unter Verwendung der nasalen Formulierung 1 etwa 31,9% 2,7

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References Bhasin S, Brito JP, Cunningham GR, et al

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2.5 Changes in the vascular system (both blood and lymphatics) It is theorized that vascular dysfunction leads to excessive interstitial fluid accumulation in lipedema tissue, promoting adipose tissue expansion (Poojari et al., 2022)