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The GLP-1 class includes drugs FDA-approved for type 2 diabetes (since exenatide in 2005) and for chronic weight management (liraglutide / Saxenda in 2014)

The theory behind microdosing is that a smaller dose still activates those pathways enough to see benefits, without triggering the aggressive nausea, fatigue, and hair thinning that higher doses can cause

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touchREV Endocrinol, 18(1), 10-19

Reconstituted compounded semaglutide belongs in the refrigerator and is generally used within 28 days

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