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Over the past few years, the conversation around GLP-1 receptor agonists has been dominated by extremes: dramatic weight loss in clinical trials, before-and-after transformations on social media, and a public discourse that has oscillated between miracle and backlash

Neuroimage 181 , 279291 (2018)

Reducing the number of variables in these improves the stability of some published estimates

Anyone with chronic kidney disease, a history of kidney stones, or reduced kidney function should have their renal function assessed and discuss suitability with their GP or renal specialist before starting, just as they would for the injection

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Anything showing massive change in 4-8 weeks is either steroids, photoshop, or exceptional circumstances