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The intracellular Km for carnitine, which is also important for understanding the mechanism of carnitine traffic has been measured only in proteoliposomes, an experimental system which gives access to the internal face of a transporter (Scalise et al., 2013)

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PLoS ONE 8:e82105 Lamhonwah AM, Hawkins CE, Tam C, Wong J, Mai L, Tein I (2008) Expression patterns of the organic cation/carnitine transporter family in adult murine brain