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Although covalent linkages are necessary to stabilize the native tertiary structure of most polypeptide proteins, those that form by degradation can produce undesired crosslinks between protein moieties, which can lead to irreversible aggregation

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Use is restricted to qualified professionals operating within licensed research facilities

Subjective improvement if any would most likely involve reduced pain signals and decreased swelling rather than structural tissue repair

doi: 10.1093/nar/gky1000 45 KaderA