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Drugmakers D2C platforms for GLP-1s debuted just last year, and outside of major players like Amazon, consumer awareness of digital pharmacies generally remains low, per a July 2025 JD Power survey

Individuals with a history of certain medical conditions, such as pancreatitis or thyroid tumors, should not use it

Semaglutides once-weekly dosing, efficacy in blood glucose control, and potential benefits in weight management make it an attractive option

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Clinical experts are a critical part of the review team and are involved in all phases of the review process (e.g., providing guidance on the development of the review protocol, assisting in the critical appraisal of clinical evidence, interpreting the clinical relevance of the results, providing guidance on the potential place in therapy)