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Introduction The spread of antibiotic resistance in the hospital environment and in community settings particularly where biofilms are involved, has spurred development of new strategies to design innovative therapeutics to curtail the spread of resistance

Four pairs of BsNbs including PV2-S26 + PV3-S77, PV2-S26 + PV3-S85, PV2-S71 + PV3-S77 and PV2-S71 + PV3-S85 were constructed and purified by size-exclusion chromatography (Fig

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