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Fermented foods that support gut health, such as yoghurt and kefir A balanced diet that supports gut health may help optimise natural GLP-1 activity

Additionally, because NAD+ supports metabolic pathways, some practitioners recommend taking a methyl donor supplement (such as TMG, trimethylglycine) concurrently, to aid in processing any excess nicotinamide produced

Taken together, the GLP-1 experience illustrates both the promise and the limits of peptide pharmacology

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Weight Loss Potential Tirzepatide has been shown to lead to greater weight loss in clinical trials