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Using the bioactive form adds a marginal advantage

Here we show that under our experimental conditions in vitro, HGF adopts an enhanced form with dynamically increased receptor-binding affinity and nitration-dysfunction resistance through interaction with lipoic acid trisulfide (LASSS)

doi:10.1089/acm.2020.0315

To investigate whether Cr GPDH could affect this lipid accumulation, we expressed Cr GPDH in two widely used ccRCC cell lines, 786-O and Caki-1

Arabidopsis GR1 and GR2 possess 8 and 9 cysteines respectively but only the two catalytic cysteines at position 73 and 78 in AtGR1 are strictly conserved and Cys73 was reported as being subject to nitrosylation (Figure 3 and Supplementary Table 4

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