Injection Site Reactions: Redness, swelling, or mild pain at the injection site are possible and typically resolve quickly with proper injection techniques
N.DargenioC.CastellanetaS.De GiacomoA.LaguardiaM.SchettiniF.et al (2023)
Almost comparable to whats seen with some surgical interventions: Participants lost up to 20.9% of their body weight on the highest dose (15 mg) 91% lost at least 5% of their body weight More than half lost 20% or more, and over a third dropped 25% or more Waist size, blood pressure, insulin resistance, and cholesterol all improved Most side effects (like nausea or constipation) were mild and appeared mostly during the dose adjustment phase
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Unlike incretin-based therapies, Cagrilintide primarily works through the amylin signaling pathway to influence appetite and body weight regulation