Q4: Why is medical supervision important when combining supplements and prescription medication
Commercially available 1-stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine, 1-stearoyl-2-15(S)-HETE-sn-glycero-3-phospho-ethanolamine (Cayman Chemicals), 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethano-lamine, 1,2-dioleoyl-sn-glycero-3-phospho-ethanolamine, 1-palmitoyl-2-(5-oxo-valeroyl)-sn-glycero-3-phosphocholine, 1-palmitoyl-2-(9-oxo-nonanoyl)-sn-glycero-3-phosphocholine (Avanti Polar Lipids) were used as reference standards
How can we think that manipulating our GLP or GIP production in such drastic ways would not have a downstream impact somewhere else
As a selective GLP-1 receptor agonist it engages receptors in the pancreas and central appetite-regulating regions of the brain, and in research it is studied for effects on satiety, food intake, glycemic control and body-weight reduction the compound anchoring the STEP obesity and SUSTAIN diabetes trial programs
However, these studies excluded patients with a history of major depressive disorder and suicidal ideation, limiting the generalizability of their findings
Response: We thank this commenter for the support for this mode of data collection
