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Sowa JP, Gerken G, Canbay A (2016) Acute liver failure - its just a matter of cell death

The foundation of AR-directed therapy lies in either the withdrawal of the natural ligand, the so-called androgens, or the direct deactivation of the AR by so-called antiandrogens (e.g., apalutamide, enzalutamide, or darolutamide) [181,182]

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NFT pretreatment resulted in a marked shift of LD 50 toward higher concentrations of either NFT or paraquat required for the induction of cell damage compared to cells without pretreatment