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Factors such as surgery, anesthesia, and stress can further compromise the integrity of the intestinal mucosal barrier, leading to the translocation of bacteria or their products (e.g., lipopolysaccharide, LPS) into the bloodstream, which becomes a significant source for triggering or exacerbating the systemic inflammatory response (65)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Spadaro D., Yun B.W., Spoel S.H., Chu C.C., Wang Y.Q., Loake G.J

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