According to the UK SmPC, the most common side effects include: Nausea (very common, affecting more than 1 in 10 people): Usually most pronounced during the first few weeks of treatment and often diminishes with continued use Diarrhoea (common, affecting up to 1 in 10 people): Typically mild to moderate in severity Vomiting (common): More frequent at higher doses Constipation (common): May occur alongside other gastrointestinal effects Abdominal pain or discomfort (common): Relatively frequent during treatment initiation Decreased appetite (very common): An expected effect related to the medication's action Dyspepsia/indigestion (common): May contribute to discomfort after eating Beyond gastrointestinal effects, other recognised adverse reactions include injection site reactions (redness, itching, or swelling at the subcutaneous injection site), fatigue , and dizziness
Glucagon-like peptide-1 receptor agonists as potential myelination-inducible and anti-demyelinating remedies
A small randomized, double-blind trial that compared a high-fat with a high-carbohydrate hypercaloric diet and an isocaloric control diet reported more adverse events during the 6-months high-fat hypercaloric diet, including weight loss (167)
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EXPIRATION DATE Present on each individual ampoule
402 Different pharmacological methods have been applied to restore E/I imbalance, such as mGluR5 antagonist treatment, NMDAR agonist treatment and GABAR agonist treatment
