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Long-term treatment of alcoholic liver disease with propylthiouracil

Orforglipron (Eli Lilly) is the first non-peptide oral GLP-1 receptor agonist a small molecule rather than an injected peptide, with no SNAC absorption-enhancer required and an FDA decision is anticipated in 2026

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In agreement with this, the ability of PA to protect cells against oxidative stress has been associated with inhibited ROS generation, increased GSH levels, and decreased lipid peroxidation (MDA), as shown in several studies (Lee et al., 2005