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ileus, intestinal obstruction, severe constipation including fecal impaction Hypersensitivity:anaphylaxis, angioedema, rash, urticaria Hepatobiliary:cholecystitis, cholecystectomy Neurologic:dysesthesia, headache Pulmonary: Pulmonary aspiration has occurred in patients receiving GLP-1 receptor agonists undergoing elective surgeries or procedures requiring general anesthesia or deep sedation

Over 12 months, both groups avoided regaining the weight they had lost

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A second study compared the occurrence of FG in patients treated with SGLT2 inhibitors (15.0 per 100,000 person-years) vs DPP4 inhibitors (9.7 per 100 000 person-years) in men 65 years and older who have T2DM using large data bases (216)

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Precise dosing is critical for obtaining the best results and ensuring safety