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However, supplementing solely with folic acid/folate can mask an underlying B12 deficiency

Second: the short plasma half-life (~30 min) was insufficient, by the time the fragment circulating in the blood was supposed to act, it had already been metabolized

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People find that they notice a non-jittery energy boost, increased clarity, and better mood for days to a week

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The B12 in the Optimal Balance Pharmacy formulation directly addresses the last factor