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HF = Heart Failure

doi: 10.1016/j.ando.2020.09.001 53 BurchHBCooperDS

The catalytic Cys groups in thiol have lower pKa values of 5.57.4, which in turn act as a H 2 O 2 -sensing center and react with H 2 O 2 under physiological conditions (Chae et al., 2023)

Semaglutide STEP 1 Trial New England Journal of Medicine (2021) Semaglutide 2.4 mg 14.9% 68 2.4% STEP 2 2 9.6% STEP 4 20 17.4% SELECT Trial (2023) Semaglutide (MACE) 20% Semaglutide HbA1c 2 1.52.0% 36 mmHg LDL-Cholesterol Semaglutide

How do I know if my current GLP-1 dose is effective

Some scientists also suspect that these drugs could act directly on tumor cells, though that hasnt yet been proven