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AGEs further modify microbial metabolic outputs and promote uremic toxin production (105)

Protein oxidation Cysteine residues in proteins are easily oxidized by ROS, reactive nitrogen species, reactive sulfur species, or GSH

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This solution containing 27.6% (w/v) Nycodenz in 3 mM KCl, 0.3 mM CaNa2-EDTA 5 mM Tris-HCl, pH 7.5 (density = 1.15 g/ml) was subsequently diluted with the same KCl, EDTA, Tris solution containing 0.75 g NaCl to produce solutions of 18.4% and 13.8% Nycodenz ( = 1.098 and 1.075 respectively)