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The results demonstrated that SIRT1 mRNA exhibited a significantly faster decay rate in the absence of SYNCRIP than in control cells, indicating that SYNCRIP plays a critical role in protecting SIRT1 mRNA from rapid degradation (Figure S9C-E)

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Periodic acid shift (PAS) reaction staining kit (Morphisto, Offenbach am Main, Germany) was used to visualize glycogen according to the manufacturers recommendations (Supplementary Fig