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Because they work on different pathways, they can often be used together to provide a more comprehensive approach to health

Continued treatment produced a statistically significant reduction in body weight compared with placebo through week 88, while the group switched to placebo regained weight

The STEP clinical trials demonstrated mean weight losses of 14.9% to 17.4% in participants with overweight or obesity, with 69% to 79% achieving at least 10% weight loss

Circulation 136:18401850 Malhotra A, Grunstein RR, Fietze I et al (2024) Tirzepatide for the treatment of obstructive sleep apnea and obesity

These are averages from controlled clinical trials

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