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United States Pharmacopeial Convention

1B and Supplementary Fig

Furthermore, geographic location, baseline selenium levels, habitual iodine intake, and disease stage may all affect an individuals reaction to supplementation [2,29,33,35,39]

(More information) Deficient/low status of riboflavin interferes with the metabolism of folate, particularly in individuals with the variant 677TT genotype in MTHFR