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Some patients may experience a change in their relationship with food, with food they once enjoyed becoming less appealing, said Stransky

Rapid titration increases side effects, which increases the likelihood of missed doses or discontinuation

Gene-specific hypermethylation of 25-hydroxylase, 1--hydroxylase, and VDR, and hypomethylation of CYP24A1 was observed in HFD-fed mice

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It works by inhibiting the NNMT enzyme, which influences fat and muscle tissue metabolism