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Genetic variations in the Sonic hedgehog pathway and clinical outcomes in bladder cancer

The recently published phase-3 clinical trials data of the drug donanemab, which targets amyloid plaque, have shown to reduce cognitive decline in AD patients, but also cause brain haemorrhage (bleeding) and edema (swelling) in some of these patients

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The brain and nervous system represent perhaps the most complex territory for any regenerative compound, yet preliminary research suggests BPC 157 may offer meaningful support here as well

Clinical trials tested for anti-AOD 9604 antibodies throughout study periods

So, the scientists wanted to find a way to get FOXO4 and p53 unstuck from each other maybe then the p53 could do its job and the senescent cell would die