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The most common dosages 31 used in studies 32 range from 2000-4000 mg of myo-inositol and 50-100 mg of d-chiro-inositol a day to match the physiological ratio that exists in the body (40 to 1 of MI to DCI 33 )

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Digestive and Liver Disease

The proposed mechanism involves NNMT inhibition increasing the SAM:SAH ratio and NAD+ precursor availability, activating sirtuin-mediated metabolic programs