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Q12: Who should not take tirzepatide

Contraindicated in patients taking opioid medications and those with seizure disorders Bariatric surgery (gastric bypass, sleeve gastrectomy) may be considered for patients with BMI 40 kg/m or 35 kg/m with comorbidities who have not achieved adequate weight loss with non-surgical methods

Proprits physico-chimiques des lipases 26Les lipases bactriennes ont en gnral un pH optimum neutre ou lgrement alcalin (8-8,5) (Lawrence, 1967) tandis que les lipases d'origine fongique ont un pH optimum neutre ou lgrement acide : 6,5 pour celle de Geotrichum candidum (Veeraragavan et al., 1990)

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Their influence is caused by the release of local inflammatory-activating products [93,95]