Sitagliptin administered to pregnant female rats and rabbits from gestation day 6 to 20 (organogenesis) was not teratogenic at oral doses up to 250 mg/kg (rats) and 125 mg/kg (rabbits), or approximately 30- and 20-times human exposure at the maximum recommended human dose (MRHD) of 100 mg/day based on AUC comparisons
As such, GLP-1 has been studied as a potential therapeutic for the treatment and management of high-impact neurodegenerative disorders, namely Alzheimers disease (AD) and Parkinsons disease (PD)
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I spaced it about 3 times per week
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Patients taking GLP-1 receptor agonists commonly report gastrointestinal side effects, including nausea, vomiting, diarrhoea, and constipation