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The answer is mechanistic

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It is studied in laboratory research for its role in fat oxidation, lipolysis, adipose tissue metabolism, lipogenesis inhibition, and cartilage repair pathway biology without the IGF-1 stimulation, insulin resistance, or receptor-mediated proliferative effects associated with full-length hGH

12 in 1998 suggests that TJs, chiefly responsible for regulating paracellular permeability, are formed primarily by the newly identified claudin family of proteins

Arch Pediatr