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I don't necessarily see it as an 'either/or' situation

doi: 10.3390/biology10010035

Scandinavian J Pain

You might have to take a B12 supplement or try a new medication

Precisely add 1.0 mL of 0.1% formic acid aqueous solution to the residue, sonicate for 1 min to dissolve the residue, and filter through a 0.22 m membrane for analysis by liquid chromatography-tandem mass spectrometry