glp 1 help with inflammation The multifaceted role of GLP-1 in metabolic disorders, chronic inflammation, and aging: Mechanisms and therapeutic potential Ozempic and other GLP-1 drugs

In fact, the active ingredients in the three GLP-1 therapies currently approved for obesity management were previously approved for diabetes under different brand names

Consistency over time is more important than a single mistake

Benefit-risk assessment of exenatide in the therapy of type 2 diabetes mellitus

Tirzepatide follows a similar pattern, with indications spanning glycemic control and obesity treatment

This would be in line with preclinical observations that incretin receptor expression is down-regulated by exposure to high glucose, and improves once normoglycaemia is restored (48), and that dys-regulation of glycaemic control in otherwise healthy humans leads to impaired incretin actions (49)

However, the consequences of this regulation remain insufficiently studied and confirmed, highlighting the need for further research in this area