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Recent findings suggest that DA by-products can conjugate with -syn, Parkin, DJ-1 and GCase, leading to loss of functions of proteins and formation of protein aggregates

Preclinical studies demonstrate that QA disrupts mitochondrial ATP production following intrastriatal administration, although it remains unclear whether this arises from direct mitochondrial toxicity or occurs secondary to ROS generation following NMDAR overstimulation [140, 141]

Study summary Zito PM, Raggio BS, Syed K

It is also naturally found in garlic and onions

Antioxidants (Basel) 10, 747

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