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The condition can also cause insulin resistance, raising risks for type 2 diabetes

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As a context, genes potentially impacted by melanocortin signaling include those involved in microglial activation, cell metabolism, protein processing, stress responses, responses to misfolded proteins, and pathways involving transforming growth factor-beta (TGF-)

MASH represents a significant health burden, with one in three people with overweight or obesity worldwide affected

Selected characteristics (including the clinical data parameters described above that were collected) were compared between treatment group cases using the chi-squared test for categorical variables and t test and one-way variance analysis for quantitative data