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High glutamine demand was first described by Eagle [11] , when he saw that cultured HeLa cells required 10 to 100 times more of glutamine than any other amino acid

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Individual variation in response is significant and poorly characterized

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Canagliflozin regulates metabolic reprogramming in diabetic kidney disease by inducing fasting-like and aestivation-like metabolic patterns

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Ng TF, Dawit K, Taylor AW

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10.1007/s10162-013-0404-1 12 CoffinA

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